Assessment of respiratory mechanics and respiratory muscles of difficult to wean critically ill patients

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Assessment of respiratory mechanics and respiratory muscles of difficult to wean critically ill patients

Methods In this observational study, 20 stable intubated patients with normal cardiac function undergoing prolonged ventilation (>10 days) in whom 3 attempts of spontaneous breathing trials failed, were evaluated. Diaphragmatic muscle function was assessed invasively by the tension-time index of the diaphragm (TTdi), an indicator of diaphragm endurance time. Additional physiologic measurements ...

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Dysfunction of respiratory muscles in critically ill patients on the intensive care unit

Muscular weakness and muscle wasting may often be observed in critically ill patients on intensive care units (ICUs) and may present as failure to wean from mechanical ventilation. Importantly, mounting data demonstrate that mechanical ventilation itself may induce progressive dysfunction of the main respiratory muscle, i.e. the diaphragm. The respective condition was termed 'ventilator-induced...

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ژورنال

عنوان ژورنال: Intensive Care Medicine Experimental

سال: 2015

ISSN: 2197-425X

DOI: 10.1186/2197-425x-3-s1-a313